Publications on Planarian Biology

Benham-Pyle BW, Brewster CE, Kent AM, Mann Jr. FG, Chen S, Scott AR, Box AC, Sánchez Alvarado A, Identification of rare, transient post-mitotic cell states that are induced by injury and required for whole-body regeneration in Schmidtea mediterranea. Nature Cell Biology 23, 939-952 (2021) DOI: 10.1038/s41556-021-00734-6

Highlighted in: Fuchs E & Ellis SJ, Stem cell progeny liasons in regeneration. Nature Cell Biology 23, 932-933 (2021) DOI: 10.1038/s41556-021-00751-5

Pre-printed as: Benham-Pyle BW, Brewster CE, Kent AM, Mann FG, Chen S, Scott AR, Box AR, Sánchez Alvarado A, Identification of rare transient somatic cell states induced by injury and required for whole-body regeneration. BioRxiv (2020). DOI: 10.1101/2020.06.04.132753

Arnold CP*, Benham-Pyle BW*, Lange JJ, Wood CJ, Sánchez Alvarado A, Wnt and TGFβ coordinate growth and patterning to regulate size-dependent behavior. Nature 7, 1-5 (2019) DOI: 10.1038/s41586-019-1478-7 * Authors contributed equally to the work

Highlighted in: Holstein, TW. What makes Flatworms go to pieces. Nature News and Views (2019) DOI: 10.1038/d41586-019-02376-z

Arnold CP, Benham-Pyle BW, Sánchez Alvarado A. Planarian Fission Induction Protocol. Protocol Exchange (2019) DOI: 10.21203/rs.2.10324/v1

Commentaries and Review

Rogers CD, Amemiya C, Arur S, Babonis L, Barresi M, Bartlett M, Behringer R, Benham-Pyle B, Bergmann D, Blackman B, Brown CT, Browne B, Camacho J, Chabu CY, Chow I, Cleaver O, Cool J, Dennis MY, Dickinson AJ, Di Talia S, Frank M, Gillmor S, Haag ES, Hariharan I, Harland R, Husbands A, Jerome-Majewska L, Koenig K, Labonne C, Layden M, Lowe C, Mani M, Martik M, McKown K, Moens C, Mosimann C, Onyenedum J, Reed R, Rivera A, Rokhsar D, Royer L, Rutaganira F, Shahan R, Sinha N, Swalla B, Van Norman JM, Wagner DE, Wikramanayake A, Zebell S, Brady SM. Pluripotency of a founding field: rebranding developmental biology. Development 151(3) (2024). doi: 10.1242/dev.202342

Benham-Pyle BW, Modified Messengers: flatworm stem cells and regeneration are guarded by RNA methylation. EMBO Journal 41(21), e112435 (2022) DOI: 10.15252/embj.2022112435

Work from Blair’s Graduate Training

Benham-Pyle BW, Sim JY, Hart KC, Pruitt BL, Nelson WJ. Increasing β-catenin/Wnt3A activity levels drive mechanical strain-induced cell cycle progression through mitosis. eLife 19799 (2016) DOI: 10.7554/eLife.19799

Tan J*, Benham-Pyle BW*, Weis W, Nelson WJ. Regulation of cadherin-catenin biology by mechanical force and phosphorylation in S. Suzuki, S. Hirano The Cadherin Superfamily (2016) * Authors contributed equally to the work

Benham-Pyle BW, Pruitt BL, Nelson WJ. Mechanical strain induces E-cadherin-dependent Yap1 and β-catenin activation to drive cell cycle entry. Science 348, 1024-1027 (2015).  DOI: 10.1126/science.aaa4559

Highlighted In: Baumann, K, Mechanotransduction: Adhesion forces promote transcription, Nat.  Rev. Mol. Cell Biol. 16, 390-391 (2015) DOI: 10.1038/nrm4017

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